Gene Screening  
Bioinformatics  
       
           
 

Our BioDiscovery software solutions are helping to revolutionise gene expression research bioinformatics. Beginning with fast, easy and accurate quantification of expression array patterns, their mission is to provide scientists with all of the tools they will need to generate, interpret and evaluate information from expression experiments; the most common of these being microarray.

A key challenge in microarray technology is to manage the massive amount of information associated with slide and high-density membrane microarray design, image processing and data mining. BioDiscovery software packages address these major issues.

CloneTracker™ keeps track of the information generated at the stages of microarray production and data base management. Subsequently, processing microarray images to obtain the quantified gene expression values from the arrays is accurately performed with the ImaGene™ software. Results can be expressed as scatter plots, histograms or by GenePie™ visualisation.

CloneTracker screen dump 1

CloneTracker screen dump 2

           
 

Finally, mining the information from the gene expression data by using GeneSight™ software, facilitates array data analysis. This analysis tool offers: principal component analysis, time series visualisation, hierarchical and neural network clustering.

GeneSight screen dump

When spot quality control and assessment is important, AutoGene™ PremiumPack can be added to the basic ImaGene Version 4.0 (or higher), processing package. With the addition of the Automation FLEXPack, the ultimate ‘walk away’ software package for microarray analysis is created, offering:

  • Accelerated speed - 10,000 spot image file load to results output in less than a minute

  • Advanced spot quality control - immediately flags empty, poor or negative spots

  • Array quality ranking - facilitates generation of visual segmentation maps

  • True walk away - easy batch compiling for 24 hr unattended operation
 
           
 

You can also further enhance your package with the following options.

ImaGene-Lite™ A semi-automated array image analysis tool for fixed format commercial arrays.
Results Reviewer™ For post analysis data viewing
CloneTracker™CE CloneTracker for the Cartesian arrayer (OEM)
CloneTracker™Affy CloneTracker for the Affymetrix arrayer
GeneSight-Lite™ For dynamic data visualisation and reporting
GP Reader™ Allows image based data files to be read into a database

Finally we are always happy to talk about customising software for your particular application.